Pegylated liposomal doxorubicin
Pegylated liposomal doxorubicin (Doxil) 20 mg/m2 iv q3w

Stewart S et al. Randomized comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma. International Pegylayted Liposomal Doxorubin Study Group. J Clin Oncol 1998; 16:683 (link to the article).

Northfelt DW et al. Efficacy of pegylated-liposomal doxorubicin in the treatment of AIDS-related Kaposi’s sarcoma after failure of standard chemotherapy. J Clin Oncol 1997; 15:653 (link to the article).

DaunoXome 40 mg/m2 iv
Q2w

Gill, PS et al. Randomized phase III study of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related KS. J Clin Oncol 1996; 14:2353 (link to the article).

Paclitaxel
Paclitaxel (Taxol) 100 mg/m2 iv over 3 hrs
Premedications:
Dexamethasone (Decadron) 20 mg iv, reduce to 8 mg iv for subsequent cycles if no hypersensitivity reaction after the first treatment
Cimetidine (Tagamet) 100 mg/m2 iv
Diphenhydramine (Benadryl) 50 mg iv
Q2w until CR, progression or unacceptable toxicity

Gill PS et al. Paclitaxel is safe and effective in the treatment of advanced AIDS-related Kaposi’s sarcoma. J Clin Oncol 1999; 17:1876 (link to the article).

Docetaxel
Docetaxel (Taxotere) 25 mg/m2 iv qw x 8 wks, then qow

Lim, ST . Weekly docetaxel is safe and effective in the treatment of advanced-stage acquired immunodeficiency syndrome-related Kaposi sarcoma. Cancer 2005; 103:417 (link to the article).

Vinorelbine
Vinorelbine (Navelbine) 30 mg/m2 iv
Q2w

Nasti, G et al. Vinorelbine is an effective and safe drug for AIDS-related Kaposi's sarcoma: results of a phase II study. J Clin Oncol 2000; 18:1550 (link to the article).

Etoposide
Etoposide (VP-16) 50 mg po qd d1-7
Q2w

Evans, SR et al. Phase II evaluation of low-dose oral etoposide for the treatment of relapsed or progressive AIDS-related Kaposi's sarcoma: An AIDS Clinical Trials Group Clinical Study. J Clin Oncol 2002; 20:3236 (link to the article).

Bleomycin + Vincristine
Bleomycin 15 IU/m2 iv
Vincristine (Oncovin, VCR) 2 mg iv
Q3w x 6 cycles

Stewart S et al. Randomized comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma. International Pegylayted Liposomal Doxorubin Study Group. J Clin Oncol 1998; 16:683 (link to the article). 

Doxorubicin + Bleomycin + Vinblastine
Doxorubicin (Adriamycin) 40 mg/m2 iv d1
Bleomycin 15 U/m2 iv d1, 15
Vinblastine 6 mg/m2 iv d1
Q4w

Laubenstein LL et al. Treatment of epidemic Kaposi’s sarcoma with etoposide or a combination of doxorubicin, bleomycin and vinblastine. J Clin Oncol 1984; 2:1115 (link to the article).